The Ozmit Sea was a large body of water separating Tal'Dorei and Issylra. Some islands on the sea were home to pirates who attacked travelers. The Isle of Glintshore was located in this sea.
The Southern regions of the Ozmit Sea, in particular, were known for their geothermal and sub-volcanic activity. The Hespet Archipelago was located near this volcanic region.
Pike Trickfoot spent four months sailing the Ozmit Sea during the time Greyskull Keep was being constructed.
Vox Machina traveled over the Ozmit Sea via skyship in the episode "Skyward" (1x15), and again in "The Chase to Glintshore" (5x11).
There are eighteen pirate companies active in the Ozmit Sea.